She dedicated most of her career to the improvement of women's health in Portsmouth and south east Hampshire, which witnessed a flourishing range of facilities and services in family planning, women's sexual health, and the management of the menopause, as a result of her determination.

[3] John Foley died in 1972 and on returning from her position as senior gynaecologist in Abu Dhabi in 1976, Margaret married general practitioner Garry O'Flynn, and so gained five step-children.

However, she had a young child by then and her husband John was now appointed consultant in obstetrics and gynaecology in Portsmouth.

[1][2] In Portsmouth, she had the opportunity to review the contraceptive services available there which were mostly run by small charities using substandard buildings.

With the help of Malcolm Roads, she obtained funding for free oral contraceptive pills for women with four or more children.

[4] Later, O'Flynn became involved in training, in particular of general practitioners, calling upon her colleagues, including Peel and Dame Josephine Barnes, as tutors.