She then attended Mount Saint Mary's College Namagunga in Mukono District for her A-Level education (1971–1972).

She also held a Diploma in computer programming from the ICL Computer School in Nairobi, Kenya, obtained in 1980, and a certificate in executive leadership from the John F. Kennedy School of Government in Cambridge, Massachusetts, United States, obtained in 1997.

She also was vice chairperson of the United Nations Task Force on Integrated Water Resource Management.

[6][1] Mutagamba served as minister of tourism, wildlife and antiquities from 15 August 2012 until being replaced on 6 June 2016 by Ephraim Kamuntu.

[11] Mutagamba died on 24 June 2017 at Case Medical Centre in Kampala from complications of liver cancer, although she also suffered from gallstones.

The burial was officiated by John Baptist Kaggwa, the bishop of the Roman Catholic Diocese of Masaka.