Mariana Grajales Cuello[1] (July 12, 1815 – November 28, 1893) was a Cuban patriot and icon of the women's rights and the fight for Cuba's independence and abolition of slavery.

Mariana, along with her family, lived in the refuge of La Delicia in the barrio Majaguabo of San Luis, Santiago de Cuba, later running a mountain settlement and improvised bush hospital.

During her time serving in the war, Mariana ran hospitals and provision grounds on the base camps of her son Antonio, frequently entering the battlefield to aid wounded soldiers, both Spaniard and Cuban.

[4][5] José Martí, after witnessing Mariana Grajales and Antonio Maceo's wife, Maria Cabrales [es], enter the battlefield to rescue the wounded Antonio, remarked: "Fáciles son los heroes con tales mujeres" (It is easy to be heroes with women such as these).

[7] In 1957, the Mayor of Havana, Justo Luis Pozo del Puerto, officially declared Doña Mariana Grajales de Maceo the "Mother of Cuba".