Marie is a town in Mississippi County, Arkansas, United States.

Arkansas Highway 14 passes through the town, leading southeast to Wilson and west 1.5 miles (2.4 km) to Interstate 55 at Exit 41.

According to the United States Census Bureau, the town has a total area of 0.15 square miles (0.39 km2), all land.

The racial makeup of the town was 69.44% White, 29.63% Black or African American, and 0.93% from two or more races.

There were 21.9% of families and 19.8% of the population living below the poverty line, including 34.4% of under eighteens and none of those over 64.