[1] She was deeply involved with the movement for Women's suffrage in the United States[2] and founded Heterodoxy, an influential feminist debating group in Greenwich Village.

She worked as assistant minister to Mary Augusta Safford in Sioux City and Des Moines, Iowa.

In 1912 Marie Jenney Howe founded the feminist literary and debating society, Heterodoxy, in Greenwich Village, New York City.

Marie Jenney Howe was taken into custody by the Secret Service in 1919 to be questioned about her radical political activities.

[4] Heterodoxy's group of feminist public intellectuals and radicals, including Charlotte Perkins Gilman, Fannie Hurst, Elisabeth Irwin, and many others, continued until the mid-1940s.