The historian Sébastien Fath sees her as "a great pioneer of this new history of African Gospel that will one day write".
In early 2016, she announces her retirement and her feeling of insecurity on BestAfrica Radio broadcast on B-One TV.
It was only in 2004, that his solo career gained momentum with the release of the album Mystère du Voile with songs like "Eh Yahweh" sung in collaboration with Mike Kalambay, "Reconnaissance", "Bilaka", etc.
In 2006, Marie Misamu went on tour out of her homeland to sing God and unite Christians around the world.
In 2008, she released the album "Mystère du Voile (Volume 2)" where we can find songs like: "Salela ngai bikamwa", "Masolo ya kati", "Associé", etc.
Then, she collaborates with other Christian musicians such as Charles Mombaya and continues to perform concerts in Africa and Europe.