The school participates in both the Ohio Valley Athletic Conference and Twin State League.

MHS is accredited by the North Central Association of Colleges and Secondary Schools and the Ohio Department of Education.

Woman's athletics include soccer, volleyball, cheer, softball, swimming, rowing, and basketball.

Students also have the opportunity to participate in the making of the school yearbook "The Orian" and a school newspaper entitled The Original is a monthly publication printed by The Marietta Times, the city's local daily newspaper.

MHS has been featured in the past on The Ellen DeGeneres Show in the segment "What's Wrong With These Signs?"