Mario Andreacchio was born in Leigh Creek, South Australia to Italian parents.

[1] He graduated from Flinders University with a degree in Psychology and went on to train as a director at the Australian Film and Television School.

[citation needed] Andreacchio has directed feature films, television specials, telemovies, children's mini-series, and documentaries.

In 1988, he won an International Emmy Award in the Children and Young People category for Captain Johnno,[2] an episode of the 1988 Touch the Sun TV series.

[1] In 2007 Andreacchio founded a film production company, AMPCO Films Pty Ltd (Adelaide Motion Picture Company), based in the Adelaide suburb of Norwood.