As an undergraduate student, Gluck worked under the supervision of William Kaye Estes on connectionist models of basic levels in category hierarchies.
The following year, Gluck and Myers proposed a theory that a wide range of superficially disparate conditioning behaviors that depend on an intact hippocampal region can be understood as being those that require adaptive changes in the underlying representation of stimulus events.
], Gluck has concentrated on understanding the fundamental principles and mechanisms of learning and memory through the integration of behavioral, biological and computational approaches.
[8] Utilizing computational modeling, Gluck has studied the effects of dopaminergic medication on reward and punishment learning in patients with Parkinson's disease.
Gluck, Myers, and their colleagues have developed hippocampal-sensitive learning tasks that predict future onset of Alzheimer's disease in humans as well as in mouse models.
[17] Gluck has established a brain research and education exchange between Rutgers–Newark and Al-Quds University Medical School in the Palestinian Territories/West Bank, which encompasses programs in basic neuroscience, clinical neurology, psychiatry, neuropsychology, and geriatrics, and is intended to lead towards the foundation of a future Palestinian Neuroscience Institute at Al-Quds University Medical School.