Mark Matthiesen is an American politician from the state of Missouri.

A Republican, he was elected in November 2016 from the 70th district of the Missouri House of Representatives, served from January 2017 to January 2019, then was elected in November 2022 from the 107th district.

Additional education resulted in an associate degree in accounting from Florida State College at Jacksonville in 1999 and a bachelor's degree in hospitality management from Missouri State University in 2005.

He is a licensed real estate agent, and in response to a 2022 candidate survey said he had worked in the hospitality industry for 20 years.

[2] In 2022, he was elected from another St. Charles county district that includes much of the city of O'Fallon.