He is a volunteer with the National Center for Reason and Justice, a non-profit organization that advocates for people who are falsely accused or convicted of crimes.

He earned a Bachelor of Arts degree in English Literature from Harvard College, after which he taught for several years in public schools.

[7] Pendergrast wrote his original arguments for Sandusky's innocence in The Crime Report in 2016 while working on The Most Hated Man in America.

[8] Freudian psychoanalysis critic, Frederick Crews, wrote an article in Skeptic magazine detailing the Sandusky case, primarily using arguments from The Most Hated Man in America.

[9] Joseph Stains reviews Pendergrast's 2017 book The Most Hated Man in America: Jerry Sandusky and the Rush to Judgement.

Pendergrast detailed the trial and did extensive research on the subject of Jerry Sandusky's 2012 guilty verdict for sexual abuse of young men at Penn State.

Stains writes that Pendergrast made a compelling case that the small-town lawyer Sandusky chose to represent him and a prosecution that relied on repressed memories, no physical evidence and possible financial motives may have been the factors that led to the court finding him guilty.

[10] Inside the Outbreaks is about the Epidemic Intelligence Service (EIS), which is part of the Centers for Disease Control and Prevention (CDC).

He has spoken at scientific and journalism seminars, book festivals, public events, and on college campuses and has appeared on various television and radio programs, including The Today Show, All Things Considered, Marketplace, and Fresh Air.

He is a volunteer for the National Center for Reason and Justice, a nonprofit organization which works with innocent people falsely accused or convicted of child abuse (related to the subject of his book Memory Warp).