A prominent member of the Internal Macedonian–Adrianople Revolutionary Organization (IMARO), Lerinski was the first person to propose a common anti-Ottoman uprising in Macedonia and Thrace.

Gyurov was born in Kotel in Ottoman Rumelia (Northern Thrace), today a town in central eastern Bulgaria.

In 1895, he left the Bulgarian Army to join the Supreme Macedonian–Adrianople Committee and take part in its 1895 organized anti-Ottoman action, which involved the burning of Dospat.

Thanks to Lerinski's military training and his organizational abilities, his armed detachment became what was essentially a school for voivodes and members for the entire IMARO.

[1] According to fellow IMARO member and writer Hristo Silyanov, Marko Lerinski turned Lerin into "... a region of model in every respect.