It details a fictional day in the life of Marlon Bundo, pet rabbit of Vice President of the United States Mike Pence, father of Charlotte and husband of Karen.

The book is an educational story explaining to children what the job of Vice President of the United States entails as seen through the eyes of the Pence family pet rabbit Marlon Bundo.

[4][5] Proceeds from the book's sales were to be donated to Tracy's Kids – an art therapy program Karen Pence brought to the Riley Hospital for Children in Indianapolis – and The A21 Campaign, a nonprofit organization working to end human trafficking.

[11] One week after the book's launch date, Regnery Publishing reported that Marlon Bundo's A Day in the Life of the Vice President was in its third printing, totaling more than 100,000 copies.

[16][17] Similarly, Susie Wilde of The News & Observer praised the illustrations and criticized the writing, "Pence shows her skill at realistic watercolors and captures the cuteness factor of the real BOTUS....

[21] A Day in the Life of Marlon Bundo is billed as an actual children's story about marriage equality and democracy, rather than as a straight-up parody of Charlotte Pence's book, yet it includes some "definite digs"[22] at the vice president.

"[25][26] The official Marlon Bundo Instagram account also referred to Twiss' book in a positive light, stating "Not gonna lie, I do look pretty fly in a bow tie.

[28] Conversely, Regnery Publishing initially criticized the release of A Day in the Life of Marlon Bundo, saying that it was "unfortunate that anyone would feel the need to ridicule an educational children's book and turn it into something controversial and partisan.