Martha Isaacs, later Higginson (active by 1771; died 1840) was an English painter.
She exhibited miniature paintings, pastels, and other works at the Free Society beginning in 1771.
She produced a number of miniatures of British subjects while in that city, including a portrait of Hickey.
It was in Calcutta that after her conversion she married, in 1779, Alexander Higginson, a member of the East India Company from an old military family; her baptismal record describes her as "a Person of riper Years".
The couple returned wealthy to England in 1782, but poor investments led their fortune to be greatly diminished by the time of Higginson's death in 1793. they had three sons, including Charles Harwood Higginson (1784–1824), a judge in the Supreme Court of Calcutta; Alexander (1786–1855) and George Powell Higginson (1788–1866) both served in the Grenadier Guards.