It serves students living in central Laredo.

The school is adjacent to the Laredo Civic Center.

Laredo High School, the first public school in Laredo, was founded downtown in 1916 at the site of the present day La Posada Hotel.

In 1937, Laredo High School was moved to San Bernardo Avenue and renamed Martin High School.

[citation needed] The Dr. Dennis D. Cantu Health and Science Magnet School focuses on health and science education, with two career paths available.