The original St. Augustine campus was located in downtown in San Agustin Historical District in Laredo, Texas.

St. Augustine High School, a college preparatory institution, bases its curriculum on the State of Texas' Distinguished Achievement Plan (DAP) with the following courses: These courses collectively give every student at St. Augustine High School a total of 28 credits.

Advancement Placement courses offered include Biology, Calculus, Environmental Science, English and World History.

Traditionally, all St. Augustine graduates apply, are accepted, and attend college - whether in Texas, throughout the U.S, or internationally.

Top destinations include: Graduates have also attended: Class rank and GPA are calculated numerically each semester based upon a traditional 100 point scale.

One Class of 2011 student was named National Hispanic Scholar, while one earned the Gates Millennium Award.