From 2020 to 2022, Poggio also served as co-director of the National Center of Competence in Research (NCCR) QSIT.

After receiving his doctorate, he began work as a postdoctoral fellow at the Center for Probing the Nanoscale, a joint research centre of Stanford University and IBM.

Until the end of 2008, he worked on high-sensitivity magnetic resonance force microscopy in Dan Rugar's laboratory at the IBM Almaden Research Center in San Jose, and he was appointed as an assistant professor in the Department of Physics at the University of Basel in summer of that year.

In this context, nanomechanical sensors are used to take highly sensitive measurements of force, spin and charges on matter.

The mechanical "top-down" devices that are traditionally found in the semiconductor industry are now joined by a new class of self-assembled "bottom-up" structures that offer huge potential for improving sensitivity.