Martinsburg station is a railway station in Martinsburg, West Virginia, United States, served by MARC Brunswick Line commuter rail service and Amtrak Floridian intercity rail service.

It is a contributing property to the Baltimore and Ohio and Related Industries Historic District.

The B&O continued to provide limited commuter service, with Martinsburg the western terminus for one of the three daily round trips.

The Cincinnati–Washington Shenandoah was introduced on October 31, 1976; the Blue Ridge was cut back to Martinsburg and rescheduled to act as an additional commuter train.

[7]: 42  The Blue Ridge was transferred to MARC in 1986, becoming part of the ex-B&O Brunswick Line commuter service.