Editor Bill Rosemann described how the concept came about: A couple months ago a few of us in the office were talking about Marvel Zombies and about where we could take the story next.

That led me to a conversation with fright master Fred Van Lente, who quickly dreamed up the creepy question of: Just where did those flesh-eaters disappear to after they were teleported into oblivion.

However, alerted by his presence, Kingpin hires the Sinister Six — Kraven The Hunter, Mysterio, Electro, The Vulture, Doctor Octopus and Sandman to create a distraction so he can steal the tablet.

The fourth issue follows the return of Earth-Z's Hulk to the Blue Area of the Moon years after Zombie Wolverine's attack on Japan and following his banishment to Sakaar by the Illuminati.

However, reverting to his zombified human form, Hulk takes advantage to infect Sentry as well, leading Zombie Spider-Man to realize that things have gone too far and that they must act now.

Years after Hulk's attack on NYC, Earth-Z has suffered the same fate Earth-2149 endured and there is no longer life on it, with the Avengers (Sentry, Moon Knight, Thundra, Quasar, Super-Skrull, Namor, Quicksilver) revealed to have killed Earth-2149's Wasp, Luke Cage and Black Panther while Zombie Giant-Man is working on a dimensional teleporter to devour more universes.

Falling through an interdimensional portal, from the "Pearly Gates," alongside Ash Williams; and materializing aboard the Asteroid M of Earth-2149's Magneto (who subsequently—and misguidedly—exploited him as a bio-hazard weapon against the normal humans of the latter world).

The series has been collected into a single volume: James Hunt reviewed the first issue for Comic Book Resources and expressed concerns that "the zombie fad is winding down, and the joke here seems to be how long a one-joke concept can be kept walking even though it's dead on its feet."