[2] One notable effect is the absence of the Ultimate incarnation of Nick Fury from his home reality, as he is given over to the custody of the Squadron Supreme in the series finale.

This absence is already present in the Ultimate Spider-Man story arc "Death of a Goblin", where Carol Danvers has taken Fury's place as the commanding officer of S.H.I.E.L.D.

The Fantastic Four defeat the Serpent Squad, an all-female supervillain team attempting to infiltrate Project Pegasus at the Devil's Point, Wyoming facility.

As the captured Serpent Squad is led away by authorities, one member admonishes Ben as a freak who will die alone, renewing his grief over his irreversible condition and Reed Richards' promises to reverse the transformation that turned him into the Thing.

Director Nick Fury refuses, not wishing to risk inter-dimensional security solely to potentially cure Ben Grimm.

Days later, as the team view prototypes for Fantastic Four action figures, the roof of the Baxter Building is ripped open by a massive explosion, heralding the sudden appearance of a group of costumed superheroes, the Squadron Supreme.

Spider-Man and Kitty Pryde swing through Manhattan when they encounter the smoldering ruins of the Baxter building, atop which the Fantastic Four are battling the Squadron Supreme, who speak only in garbles and cannot fully control their powers.

Kitty calls the X-Men for assistance moments before Nick Fury and the Ultimates drop out of the sky, declaring the Squadron Supreme under arrest.

The X-Men arrive and enter the full-scale superhuman brawl just as the Squadron Supreme adjust to the new dimension and declare Reed Richards under arrest for his crimes against humanity.

Back on the ground Reed Richards, being escorted to a more secure location, peeks outside an air vent to notice the Ultimates locked in a titanic battle with the Squadron Supreme.

Helicarrier, Fury suits up for battle before conferring with the unseen conspirator, outlining his plan to steal the probes and to escape back to the Ultimate universe.

Spider-Man awakens Fury, and both rush to the bridge to see that Doctor Doom, revealed as the unseen conspirator, has defeated the Squadron Supreme and the Ultimates and is ready to conquer the Supremeverse.

The alien organism raging across the country is the result, with Richards' probes serving as a scapegoat to eliminate the trail to the Defense Department.

Before they can escape, the roof disintegrates, leaving Richards and the X-Men staring at Squadron Supreme of Earth-712, who declare that their world too was destroyed; they also demand answers.

Back in the Ultimate Universe, Captain America discusses the considerable power of Scarlet Witch's abilities and mentions that Carol Danvers is in the front-running to become the new leader of S.H.I.E.L.D.