As Assistant Director of LIGHT Gallery, New York (1971–1974), Director of Castelli Graphics and Photographs, New York (1975–1982), an artist representative (1982–1988) and an independent curator (1989–present), Heiferman has organized influential[citation needed] thematic exhibitions and worked with a wide range of artists and photographers including Eve Arnold, Garry Winogrand, Robert Mapplethorpe, Stephen Shore, Lewis Baltz, William Eggleston, Robert Adams, Nan Goldin, John Waters, and Richard Prince.
Known as an early champion of color, narrative and appropriation (art) photography, Heiferman shifted the focus of his work in the mid-1980s to develop projects explored the impact of mediated and vernacular images on history, society, culture and everyday life.
[1] In 1991, Heiferman became a founding partner (with Carole Kismaric) of Lookout, a company that, for a dozen years, produced innovative exhibitions and cultural projects for major museums (including Fame After Photography, Museum of Modern Art, 1999), humanitarian organizations, publishers, and imaging and media corporations.
A contributing editor to Art in America, Heiferman has also written for publications including Artforum, Bomb Magazine, Bookforum, "Photoworks", and ARTnews.
He is a core faculty member in the International Center of Photography/Bard College MFA Program in Advanced Photographic Studies, and teaches in the School of Visual Art's MFA Program in Photography, Video and Related Media.