Mary Anne Estlin (31 July 1820 – 14 November 1902) was a British abolitionist and leading figure in anti-slavery and anti-prostitution campaigns in Britain.

She and Eliza Wigham were active in the campaign in England and in 1863 they both served on Clementia Taylor's Ladies' London Emancipation Society.

[1] There was a schism within the abolitionists between the radical views of William Lloyd Garrison and the more conservative position of the British and Foreign Anti-Slavery Society, who was content to see a gradual end to slavery.

Eliza Wigham and Jane Smeal of the Edinburgh Ladies' Emancipation Society supported Estlin's initiative to find common ground between the Garrisonians and the BFASS.

[4] Mary Anne Estelin died aged 82 on 14 November 1902 in her residence, 36 Upper Belgrave Road, Clifton, Bristol.