In 1884 Mrs. Isabel Baker and Miss Bessie Baker had been responsible for bringing out a number of sisters of the Dominican Order, who had intended to follow the nursing profession at the deceased Governor Daly's residence on the corner of Ward and Hill Streets in North Adelaide, but owing to unforeseen circumstances, they were not able to do so.

[2] Drs Edward Willis Way and James Alexander Greer Hamilton (1854–1925[3][4]) were the principal surgeons at the North Adelaide Hospital.

[5] Much of the hospital is heritage listed, maintaining its turn of the century exterior and interior.

It features a large maternity wing, 8 operating theatres, day surgery suite, 1 medical ward including a day infusion centre, two surgical wards all supported by a Level II Intensive Care Unit.

The hospital also houses the extensive Mary Potter Hospice, a 15-bed hospice caring for palliative care patients, and a comprehensive Oncology Centre, a radiology department, and also multiple specialist suites within or adjacent to the hospital.