In 1909, she moved to the east coast to study at Vassar College, graduating with a Bachelor of Arts in 1913.
Around her time spent studying at University of Minnesota, she met Matthew Givens Reynolds.
Her family encouraged her to settle down again and remarry, but she found this an unsatisfying option in the wake of her husband's death.
[1] Once settled in Paris, she quickly became a popular socialite due to her association with novelist, painter, and poet Laurence Vail.
Though she did not share a working studio with Duchamp, their mutual house was considered itself an extravagant aesthetic affair and frequently hosted the literati and artists of the time.
Notably, she helped the artist Jean Hélion hide from the Nazis after he escaped from a German prisoners camp in 1942.
During this time period, her interest in bookbinding waned, and between 1945 and 1947, she primarily worked as a Paris representative for the arts magazine View.
[7] Her health gradually waned from the stresses taken during her escape from the occupation, and in April 1950 she checked into the American Hospital in Neuilly.
On September 30, 1950, she died from endometrial cancer in her home in Paris, with Marcel Duchamp at her side.