The highway was extended west part of the way to White's Ferry in the late 1920s and early 1930s.

White's Ferry Road continues across the river in Loudoun County, Virginia, as Virginia State Route 655, which leads to U.S. Route 15 (James Monroe Highway) north of Leesburg.

[2] MD 107 heads east as a two- to three-lane undivided street through the Poolesville Historic District.

MD 107 passes the historic farm complex Darnall Place near its crossing of Dry Seneca Creek.

[1][3] MD 107 was constructed as a 12-foot-wide (3.7 m) old-bound macadam road by Montgomery County with state aid from Dawsonville to Poolesville between 1916 and 1918 with the purpose of connecting Poolesville and Washington, D.C., with a modern highway.