The state highway runs 1.54 miles (2.48 km) from Woods Road south of MD 100 north to MD 173 in Jacobsville in Anne Arundel County.

Magothy Bridge Road continues south and west as a county highway toward a crossing of the Magothy River and on to Pasadena.

MD 607 heads north as a two-lane undivided road and temporarily becomes a divided highway around its intersection with MD 100 (Paul T. Pitcher Memorial Highway).

MD 607 continues north as Hog Neck Road to its northern terminus at MD 173 (Fort Smallwood Road).

[5][6] The entire route is in Jacobsville, Anne Arundel County.