The building was originally an arrowroot factory built in the mid 1800s that was renovated between 2004 and 2008 into a 16,000 square foot purpose-built museum.
Part of the remaining original structure is home to the Arrowroot Gift Shop, which features art and crafts created by local artisans.
Homer's Café which offers baked goods and lunch items, and also serves as a space to exhibit and sell local artists' work.
The museum also holds objects relating to Bermuda's history and culture in the form of vernacular and fine-art photographs, sculpture, and historic documents and ephemera.
Notable holdings include works by Winslow Homer, Georgia O'Keeffe, Albert Gleizes, Henry Moore, Marsden Hartley and Yousuf Karsh.