Matías Nicolás Caruzzo (born August 15, 1984, in Buenos Aires) is an Argentine former football defender.

Caruzzo came through Argentinos Juniors youth development system to make his professional debut on March 25, 2006, in a 3–1 away defeat to Gimnasia y Esgrima de Jujuy.

Caruzzo was an important member of the Argentinos Juniors team that won the 2010 Clausura championship.

Boca paid Argentinos a 2,500,000 US dollars fee, plus a percentage of a future sell.

[2] In January 2014, Caruzzo signed a contract with Universidad de Chile for 3 years.