Mateo De Angulo Velasco (born June 18, 1990, in Cali) is a Colombian swimmer, who specialized in long-distance freestyle events.

De Angulo helped his Colombian team to take the trophy in the 800 m freestyle relay at the 2010 Central American and Caribbean Games in Mayagüez, Puerto Rico.

[3] De Angulo qualified for the men's 400 m freestyle at the 2012 Summer Olympics in London, by establishing a Colombian record and a time faster than the FINA B-cut off time of 3:53.66 from the Indy Grand Prix in Indianapolis, Indiana.

[4][5] He challenged former world champion and USC Trojans swimmer Mateusz Sawrymowicz of Poland, Florida Southern Moccasins swimmer Allan Gutierrez Castro of Honduras, and Palestine's Ahmed Gebrel on the first heat.

De Angulo failed to advance into the final, as he placed twenty-sixth overall on the first day of preliminaries.