Mathematics and the Search for Knowledge is a 1985 book by Morris Kline about the role of mathematics in understanding physical reality.

It is preceded by Kline's work, Mathematics: The Loss of Certainty.

In the book, Kline gives an outline of the development of physics, beginning from ancient Greek astronomy.

He explains that modern physics (consisting of theories such as electromagnetism, relativity and quantum mechanics) differs from previous fields such as Newtonian mechanics in that it consists of purely mathematical models that cannot be intuitively visualized.

Thus, Kline argues that it is mathematics that provides a true understanding of physical reality, rather than our senses.