Boselli began his career at Argentine First Division clubs Boca Juniors and Estudiantes before moving to England in 2010 to join Wigan Athletic.

"[3] Boselli is a two-time Copa Libertadores winner, being champion with Boca Juniors in 2007 and with Estudiantes de La Plata in 2009.

[5] Boselli began playing small sided football at Sportivo Pereyra de Barracas and then to the youth system of All Boys.

[11][8] In this task, however, many youth team players made their presentation seeings as the starting squad were celebrating winning the 2003 Copa Libertadores days earlier.

[12] In 2004, Boselli formed a Boca Juniors winning team with Carlos Tevez, Guillermo Barros Schelotto, Pablo Ledesma, Diego Cagna, Sebastián Battaglia, Jonathan Fabbro, Rolando Schiavi, Roberto Abbondanzieri, youth graduate Neri Cardozo and Colombian Fabián Vargas.

[8] At Málaga, Boselli was one of three South American players in the team, including Peruvian Juan González-Vigil and Brazilian Tiago Marchiori.

[15] After returning to Boca Juniors, Boselli struggled to become a regular in the first team, being behind Martín Palermo and Argentina 2006 FIFA World Cup player Rodrigo Palacio in the coaches' consideration.

[5] Whilst at Boca, the club rejected many loan offers and permanent signing deals, including from Lazio and Catania, always saying that Boselli was not for sale.

[20] Having struggled to adapt to English football, Boselli was loaned to Italian Serie A side Genoa on 13 January 2011 for the remainder of the 2010–11 season.

[24] Before returning to Wigan from his season-long loan at Genoa, Boselli expressed interest in a permanent move to the Italian side.

[27] Boselli finished as the club's top goalscorer in both the Apertura and Clausura tournaments, featuring in 29 games and netting 11 goals.

[32] In the post match interview following the FA Cup game against Macclesfield on 26 January 2013, Wigan manager Roberto Martínez confirmed that Boselli had agreed to a further loan spell, this time back in Italy at Palermo.

[35] For 2019, Boselli disputed 26 games, scored 8 goals and gave two assistances for Corinthians between the local tournament and the Copa Sudamericana, he also won the 2019 Paulista Championship.

[36] In September 2021, Boselli departed to Argentina for family matters with permission from Cerro Porteño and was absent from the team,[37][38] which resulting in the passing of his mother as communicated by the club.

[42] In 2005, Boselli was part of the Argentina U-20 national team that finished third in the South American Youth Championship (therefore qualifying for that year's U-20 World Cup).

On 27 September 2009, Boselli was called for a local league based Argentina national team (replacing injured Esteban Fuertes) to play a friendly match against Ghana.