She then demonstrated against Joseph Califano, the Secretary of Health, Education, and Welfare in 1977–1979 (SITE), over reproductive rights among other related topics.

As the Lesbian Action Committee evolved, they wanted to work with the Reproductive Rights National Network to present information about lesbian-focused material.

Despite their intentions, some people in CARASA didn't want this type of publicity, distancing themselves from Wolfe and the Lesbian Action Committee.

Because the Human Life Amendment was being considered by Congress, some members of the group participated in civil disobedience by disrupting the hearings in Washington, which resulted in arrests and convictions.

This coalition held a conference over the Family Protection Act and began doing demonstrations about the Human Life Amendment and many other things.

In 1985, the Gay and Lesbian Alliance Against Defamation (GLAAD) was created, and Wolfe attended the first public event in connection with the AIDS crisis.

Because of Wolfe's previous political experience, she led the way in getting ACT UP involved in policy instead of just advocacy to continue this mass movement.

[4] In Let The Record Show: A Political History of ACT UP New York, 1987–1993, Sarah Schulman writes, "Scanning the interviews I conducted with a wide range and demographic of ACT UPers, the two names that emerge most often in reference to internal leadership are clearly Maxine Wolfe and Mark Harrington...these two were repeatedly named as profound influences.