The Mayo Clinic Health System Event Center is a 5,280-seat (8,200 for concerts) multi-purpose arena in Mankato, Minnesota, built in 1994[2] and opened in early 1995.

In the 1992 general election, Mankato voters approved a 0.5% tax increment to support downtown renovations, including construction of a new sports arena.

[4][5] The south side of the complex incorporates the restored exterior of the First National Bank of Mankato, a 1913 Prairie School building.

[13][14] On December 30, 2019, the City of Mankato announced a new naming rights agreement with Mayo Clinic Health Systems effective January 1, 2020.

Notable past artists and events include Aerosmith, Disney Live, Elton John, James Taylor, Jeff Dunham, John Mellencamp, Kenny Rogers, KISS, Monster Jam, Tom Petty, Weird Al Yankovic and WWE Live.