McDonald Chapel is a census-designated place in Jefferson County, Alabama, United States.

[3] According to the U.S. Census Bureau, the CDP has a total area of 1.1 square miles (2.8 km2), all land.

As of the 2020 United States census, there were 739 people, 224 households, and 123 families residing in the CDP.

There were 448 housing units at an average density of 413.0 per square mile (159.5/km2).

23.7% of all households were made up of individuals, and 12.3% had someone living alone who was 65 years of age or older.