McIntire Run is a 4.11 mi (6.61 km) long 2nd order tributary to Big Sandy Creek in Fayette County, Pennsylvania.

McIntire Run rises about 2 miles south of Summit, Pennsylvania,[2] and then flows southeast to join Big Sandy Creek about 3 miles north-northeast of Elliottsville.

[3] McIntire Run drains 3.27 square miles (8.5 km2) of area, receives about 51.2 in/year of precipitation, has a wetness index of 313.93, and is about 95% forested.

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