[9] Motu sister Sally fought at the Golden Gloves event in Queensland in 2016, unfortuanately Mea was unable to compete due to injury.

[13] Motu made her television fight debut when she took on Sally Kaokao at Sky City Theatre in November 2020.

[12] Motu won the fight by third round stoppage in dominating fashion winning her first professional boxing title.

[23] Jenkins is a former New Zealand National (Pro Box NZ version) Welterweight champion which she won on a Joseph Parker undercard in December 2018.

[24][25] Motu will not only win both fights against Jenkins, she will also capture her second New Zealand title, but this time in the Super Lightweight division.

In August 2021, Motu finished off her year with a fight against Māori professional boxer Rangi Hetet.

[30] If Motu won the fight, she would break a 14-year record that Daniella Smith set that was tied with Lani Daniels, Geovana Peres, and herself.

[35][36] After the fight, Motu made her intentions clear that she wanted to take on New Zealand born Australian, IBF World Super Bantamweight champion Cherneka Johnson.

[39] On 19 August, Motu took on Thailand National Bantamweight champion Thanchanok Phanan for the vacant PBCNZ International Featherweight title.

[44] On 26 November, for the first time in her professional career, Motu fought overseas against undefeated Iran boxer Nastaran Fathi.

[45] Motu won the fight by Split Decision, winning the vacant WBC Asian Boxing Council Continental super bantamweight title.

[46] At the end of December 2022, Motu finished her boxing 2022 year with receiving a ranking of 7th[47] in the WBA and 16th in the WBC in the Super Bantamweight division.

[48] In March 2023, it was announced that Mea Motu will fight for the vacant IBO World super bantamweight title against canadian boxer Tania Walters.

[50] On 27 April 2023, Mea Motu won the fight by unanimous decision, becoming the third Māori to win a World Boxing title.

[61][62] Motu unsuccessfully challenged Ellie Scotney for the WBO, IBF and Ring Magazine Super Bantamweight World titles on 26 January 2025, at Motorpoint Arena, Nottingham, England, losing by unanimous decision.

[5] In 2024, she was forced to medically retire from Celebrity Treasure Island as her high muscle mass and lack of body fat made her susceptible to hypothermia and exposed underlying respiratory conditions after the team challenge in a cold and stormy conditions was cancelled with all results annulled.