Meaghan Oppenheimer grew up in Tulsa, Oklahoma,[2] and was a former child actor, working in various regional theatre productions and television shows.

[7][8] In December of that year, ABC announced that Reese Witherspoon would be producing a new drama series for TV written by Oppenheimer, with the working title Please Don't Go, about the personal and professional life of a ruthless divorce attorney in Dallas whose past continues to haunt her.

[9] In March 2016, ABC announced that Penelope Ann Miller had been cast opposite T. R. Knight in the project[b] that in 2016 was released as Broken—a series pilot that halted production after the first episode aired.

Oppenheimer's un-filmed screenplay, The Remains, was selected for the 2013 Black List—a yearly list of "...best Screenplays not yet made into films..."[21] Dana Feldman of Forbes wrote while reviewing Tell Me Lies: "...[the production] received a straight-to-series order, and we definitely need another season..."[13] The Her Voice podcast hosts exclaimed: "From script to screen, she is clear in her purpose and powerful in her ability to manifest the right people and circumstances to be able to develop female driven stories about mental health, relationships, and generational trauma.

"[22] Keely Weiss of Elle Magazine writes: "...showrunner Meaghan Oppenheimer pulled [the adaptation] off with aplomb, turning Lovering's novel into a visually propulsive show populated by a rich cast of characters, all while preserving the core themes of the book.