Discogyne, which forms a natural grouping of 6 or 7 species within the genus all characterised by a stylar disc surmounting the ovary (lacking in other Meconopsis).

As reflected by the species etymology, M. manasluensis is endemic to the vicinity of the Manaslu Himal of Gorkha district, central Nepal, where it grows at high elevation (ca.

The closely related M. pinnatifolia is known from the same general locality in the wild, however possible mechanisms preventing cross-fertilisation between M. manasluensis and this species remain unclear.

[1] It was not until later herbarium research undertaken for preparation of the Flora of Nepal that the specimens were discovered to constitute a new species, subsequently described in 2011 alongside Meconopsis autumnalis.

The plant is locally abundant, but a small or possibly severely restricted specific distribution may give cause for conservational concern.