[12] On August 28, 2005, Medco Health Solutions contributed $5,000 to the Southwestern Oklahoma State University College of Pharmacy Scholarship Fund.

[13] In October 2005, Medco was selected as the finalist of a three-year pharmacy benefit contract for the California Public Employees' Retirement System (CalPERS) Self-Funded Health Plans to begin July 1, 2006.

[19] In 2005, Medco Health Solutions agreed to pay the United States $155 million plus interest to settle allegations that it accepted kickbacks from drug makers and submitted false claims to the government.

[23] In September 2010, Medco acquired United BioSource Corporation, a company that assesses safety risks and the value of medications when they reach the market.

[24] In April 2008, Medco acquired a majority interest in Europa Apotheek, a privately held company based in the Netherlands that provided mail-order and specialty pharmacy services in Germany.

[26] In October 2011, Medco bought out United Drug Plc's half of their British home care joint venture the companies began in 2009.

Medco's automated pharmacies were located in Las Vegas, Indianapolis, and Willingboro, NJ, and together had the capacity to fill more than three million prescriptions per week.

Medco's mail-order business generated $26 billion in 2011 net revenues and was one of the largest pharmacy operations in the United States.