[2] In 2010, the club failed in its initial attempt to qualify to the Ghana Premier League.

[2] This led to the purchasing of the defunct Kessben FC the same year.

[3] The base of the Kessben club was moved from Abrankese in Ashanti Region of Ghana to Tarkwa in the Western Region of Ghana.

[3] Medeama SC play their home matches at Akoon Park located in Tarkwa, Ghana.

[7][8] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.