In actuality, medical investigative duties in the United States are normally the responsibility of the Centers for Disease Control and Prevention (CDC) and local health departments, while the NIH is primarily a disease-research and -theory organization.

When people in New York City start turning the color blue, the NIH team is called upon to help cure this outbreak.

After years of watching young children fall prey to a crippling muscular ailment, a small community summons the NIH team to hopefully find a cure.

When adult film stars in Los Angeles start falling prey to a devastating disease, the health department summons the NIH team.

However, when a housewife falls prey to the same illness, a new link needs to be found and the answer might lie with a plastic surgeon, water and some fish.