The Medici Madonna is a marble sculpture carved by the Italian Renaissance master Michelangelo Buonarroti measuring about 88.98 inches (226 cm) in height.

Dating from 1521 to 1534, the sculpture is a piece of the altar decoration of the Sagrestia Nuova in the Basilica of San Lorenzo, Florence.

Another indication of the Virgin denying the infant Christ of her breast is shown through the girdled chiton garment she is wearing that completely conceals her.

[2] Several preparatory drawings (at the British Museum and the Albertina) show a less compact composition, in which the Madonna's legs were parallel to each other.

The composition is somewhat similar to Michelangelo's Madonna of the Stairs, with the Virgin sitting on nearly cubic block and breastfeeding the Child.