Aside from the regular clinical departments, it also has tertiary care departments such as cardiothoracic surgery, neurosurgery, advanced oncological care, radiotherapy, bone marrow transplantations, hemodialysis, a large hospital pharmacy, and a regional level I trauma center.

The hospital does not have its own trauma helicopter, but an ADAC helicopter from the neighboring German town of Rheine frequently crosses the border when the local (Dutch) ambulance control center requests it.

It is mainly an ambulatory facility, though some small low-risk surgeries which do not require more than two days of hospitalization are also performed there.

It also has a small urgent care department which is open in the morning, afternoon and evening but not at night; ambulances do not bring patients here, but drive them directly to the main facility in Enschede instead.

A number of MST specialists spend one or two days per week in Haaksbergen or Losser.