The school offers AP Level Courses in English Literature, English Language, Human Geography, U.S. Government & Politics, U.S. History, Microeconomics, Macroeconomics, Calculus, Biology, Physics, and Studio Art.

The school also offers a dual enrollment program with Thomas College in which students can earn college credit in a variety of courses including Composition I & II, Literature, Literature & Society, Calculus, Quantitative Analysis, U.S. History, Psychology, Criminal Justice, and Sociology.

[7] The MVHS Players is the drama troupe of Medomak Valley High school.

Pie is traditionally served during intermission, acquired from Waldoboro's iconic Moody's Diner.

In addition to sports, Medomak Valley offers many club opportunities to students.