Meena Upadhyaya is an Indian-born Welsh medical geneticist and a Professor emerita at Cardiff University.

Her research has focused on the genes that cause various genetic disorders, in particular neurofibromatosis type I and facioscapulohumeral muscular dystrophy.

She developed molecular tests to aid in the diagnosis of more than 20 genetic diseases including neurofibromatosis type 1.

She received the St David Award in 2017, under the Innovation, Science and Technology category, for her outstanding contribution to medical genetics.

In 2017, Upadhyaya became the first female British-Indian professor to receive Honorary Fellowship at University of Wales Trinity Saint David.

She organised the First International Conference on RASopathies and Neurofibromatoses in Asia: Identification and Advances of New Therapeutics in Kochi, Kerala, India in 2017.

Upadhyaya was appointed as a Non-Executive Director (NED) on the Welsh Government Civil Service Board (2020-2024).