Meera has also developed several hands-on physics programs for students in grades 5–12, and summer institutes for K-12 teachers.
After a post-doctoral fellowship at Max Planck Institute for Solid State Research, she arrived at the University of Missouri in 1978, where she is currently a professor in the department of physics and astronomy.
Chandrasekhar's research interests are in the area of optical spectroscopy of semiconductors, superconductors, and conjugated polymers, with an emphasis on high-pressure studies.
Beginning in 1993, she led a series of programs for K-12 students and their teachers, supported by the National Science Foundation, and the Missouri Department of Higher Education.
The programs included Exploring Physics for 5-7 grade female students, which focused on learning physics concepts through hands-on activities; Family Evenings with Science and Technology (FEST), a middle school parent and student program where each team built a miniature working drawbridge; Saturday Scientist, an industry based experience for 8-9 grade students designed to increase students' awareness of potential careers in the physical sciences; Newton Summer Science Academy for 9-11 grade girls, which integrated science, engineering and mathematics through a toy factory building project; and summer teacher academies for 5-12 grade science teachers.