[1] Megachile pruina is a species of bee in the subfamily Megachilinae, belonging to the subgenus Pseudocentron Mitchell, 1934.

[2] In 1937, a second subspecies, M. pruina nigropinguis Mitchell, was described to account for a dark female variant collected in Texas.

However, U.S. populations showed no significant genetic differences among themselves, suggesting that the formal subspecies classifications may be invalid.

Megachile pruina is found in the United States, ranging from Virginia[4] to Florida, and extending westward to Texas mostly along coastal habitats.

[6] In Bermuda, since 1989, its distribution has been confined to the Castle Harbour Islands Nature Reserve.