It is published by the Herzog College, an affiliate of Yeshivat Har Etzion, two or three times a year.

Writers and editors for Megadim include Dr. Yosef Ofer and Dr. Mordechai Sabato of Bar-Ilan University, Dr. Shmuel Wygoda (a student of Emmanuel Levinas), Rabbi Dr. Yoel Bin-Nun, Rabbi Yaakov Medan, Prof. Yoel Elitzur of Hebrew University, and other notable members of the religious Zionism movement.

Therefore, the most popular topics among the articles are literary analyses of the Bible and of Jewish commentators, which enable the adoption of scholarly approaches without needing to deal with loaded issues such as the Documentary Hypothesis or the origins of Christianity.

The articles in Megadim are strictly peer-reviewed before publication in order to maintain high standards.

One of the weaknesses of the journal is an insufficient reliance on sources written in languages other than Hebrew.