Megalenhydris barbaricina is an extinct species of giant otter from the Late Pleistocene of Sardinia.

It is known from a single partial skeleton, discovered in the Grotta di Ispinigoli near Dorgali, and was described in 1987.

[6] The structure of the teeth points to a diet of bottom dwelling fish and crustaceans.

During the Middle-Late Pleistocene Corsica and Sardinia had their own highly endemic depauperate terrestrial mammal fauna which besides Megalenhydris included the Tyrrhenian field rat, (Rhagamys orthodon) the Tyrrhenian vole (Microtus henseli), the Sardinian pika (Prolagus sardus), a shrew (Asoriculus similis), a mole (Talpa tyrrhenica), a dwarf mammoth (Mammuthus lamarmorai) the Sardinian dhole (Cynotherium sardous), a galictine mustelid (Enhydrictis galictoides), two other species of otter (Algarolutra majori and Sardolutra ichnusae) and a deer (Praemegaceros cazioti).

This article related to prehistoric animals from order Carnivora is a stub.