Meguro is predominantly residential in character, but is also home to light industry, corporate head offices, the Komaba campus of University of Tokyo as well as fifteen foreign embassies and consulates.

The Higashiyama shell mound in the north of the ward contains remains from the paleolithic, Jōmon, Yayoi, and Kofun periods.

The Meguro Fudō was one of five Fudō-myōō statues placed at strategic points on the outskirts of Edo in the early seventeenth century by the abbot Tenkai, an advisor to Tokugawa Ieyasu, to provide protection for the new capital of the Tokugawa shogunate.

Meguro ward government is led by the city assembly with 36 elected members with current terms from May 1, 2011, to April 30, 2015.

Municipal elementary and junior high schools are operated by the Meguro City Board of Education.